Belgium manager Roberto Martinez says England are favourites to win their World Cup group.
"I saw their last game against Germany (a 0-0 draw last month), and they are a good side, young, with lots of new faces".
But Southgate, recalling England's decades of disappointment on the global stage, was wary of Panama, telling the BBC: "We've been good at writing teams off and then getting beat".
In the wide-ranging interview, Southgate dismissed any concerns over potential long-distance travelling his squad may face arguing that his England players were well versed with the demands of major competitions, with numerous squad making regular visits to European counterparts during the season.
Southgate pointed to England's premature exits from the last World Cup and Euro 2016 as reasons for limiting expectations. I'm really looking forward to getting on with it now.
England's opener is against Tunisia, now ranked 27th, in Volgograd on June 18, with the game against 56th-ranked Panama in Nizhny Novgorod on June 24.
"I've got a big problem at home because my daughter is English so I need to make sure that she knows which team to support!"
But William Hill, one of Britain's leading bookmakers, responded to Friday's draw by cutting England's odds of winning the 2018 World Cup to 16/1 (bet £1 to win £16) from 20/1.
"It's a challenging group for both nations, probably the hardest one in terms of the travelling and logistics".
England were drawn with Belgium, Tunisia and Panama in Group G of the 2018 finals and will open their campaign against Tunisia on June 18 before facing Panama six days later, then closing the group with top seeds Belgium on June 28.
Tunisia will be based just outside Moscow during the tournament, and their coach is also happy at avoiding playing until the fifth day of the competition.
"With the way Panama qualified by beating the United States it will be something we have to manage. They were a very good team, but this team is more humble than them".
"It would be stupid of us to set targets".
The England manager said that Kane - who is expected to be named captain before the squad go to Russian Federation - had to deliver at a major global tournament to be considered among the world's elite.
The attack was carried out in response to high-trajectory fire at an IDF post in the northern Gaza Strip. The IDF claims it is retaliation for a mortar shelling of an Israeli outpost by another militant group.
Talib, who went to Kansas, and Crabtree, who went to Texas Tech, have had problems in the past, including an altercation in 2016 . First, you punched a Broncos opponent Chris Harris in the midsection, resulting in him being removed from the game.
Mobile also had a record day , Adobe found, saying smartphones have become the "de facto device" for on-the-go shopping. Overall web traffic to retail sites increased by 11.9 percent on Cyber Monday, with the season average at 5.7 percent.
An unnamed friend of Duysak told Buzzfeed that the former Twitter contractor didn't have any apparent interest in politics. I didn't do anything on objective . "I didn't hack anyone". "I didn't do anything that I was not authorized to do".
A spokesman for Uber told the BBC the firm is not able to clarify how many United Kingdom drivers are included in the 2.7 million. The data breach resulted in almost 11,000 Washington Uber drivers having their data compromised.
BMW says the all-electric roof opens and closes "very quietly" in 15 seconds, at speeds of up to 50 km/h (31 mph). Ivory white leather upholstery rounds out the cabins of both models, while the Roadster adds a black option.
For now obese children, the risk is higher: three out of four obese two-year-olds are predicted to still be obese at age 35. In addition, the more overweight or obese someone was as a child, the greater the person's chances of being obese by age 35.
Despite the loss, Miami will have a shot at redemption against No. 1 Clemson (11-1, 7-1) in the ACC Championship game Saturday. Auburn and Georgia will collide in the SEC Championship Game, the first to be played in the new Mercedes-Benz Dome in Atlanta.
The twitter threat hinted towards the release of the update for more HTC smartphones including the U Ultra, U11 Life and HTCH 10. The update is 1.2GB in size and brings popular Oreo features like Picture-in-Picture mode (PiP), Adaptive Icons, and more.
Kentucky woman helps with White House Christmas Decorations
In Trump's view, the move toward the use of the more inclusive "happy holidays" phrase minimized the Christian celebration. Trump, who personally selected the decor, says she wanted to make the White House feel like home over the holidays.
Fuller Leaves American Gods
Toplined by Ian McShane and Ricky Whittle, the first season of the mythological fantasy drama got off to a strong ratings start. Fuller and Green created the adaptation of Neil Gaiman's 2001 novel three years ago with it finally premiering this year .
Study finds dogs have more smarts than cats
Hunting requires a lot of energy, particularly for large predators, and the intervals between successful kills are unpredictable. And raccoons, despite their smaller brain size, had nearly as many neurons in their cerebral cortex as dogs.